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Authors are the souls of any journal, and deserve much respect. To publish a journal manuscripts are needed from authors. Authors have a great responsibility for producing facts of their work in terms of number and results truthfully and an individual honesty is expected from authors in this regards. Both ways its true "No authors-No manuscripts-No journals" and "No journals–No manuscripts–No authors". Reviewing a manuscript is also a very responsible and important task of any peer-reviewed journal and to be taken seriously. It needs knowledge on the subject, sincerity, honesty and determination. Although the process of reviewing a manuscript is a time consuming task butit is expected to give one's best remarks within the time frame of the journal.
Salient features of the JCDR: It is a biomedical, multidisciplinary (including all medical and dental specialities), e-journal, with wide scope and extensive author support. At the same time, a free text of manuscript is available in HTML and PDF format. There is fast growing authorship and readership with JCDR as this can be judged by the number of articles published in it i e; in Feb 2007 of its first issue, it contained 5 articles only, and now in its recent volume published in April 2011, it contained 67 manuscripts. This e-journal is fulfilling the commitments and objectives sincerely, (as stated by Editor-in-chief in his preface to first edition) i e; to encourage physicians through the internet, especially from the developing countries who witness a spectrum of disease and acquire a wealth of knowledge to publish their experiences to benefit the medical community in patients care. I also feel that many of us have work of substance, newer ideas, adequate clinical materials but poor in medical writing and hesitation to submit the work and need help. JCDR provides authors help in this regards.
Timely publication of journal: Publication of manuscripts and bringing out the issue in time is one of the positive aspects of JCDR and is possible with strong support team in terms of peer reviewers, proof reading, language check, computer operators, etc. This is one of the great reasons for authors to submit their work with JCDR. Another best part of JCDR is "Online first Publications" facilities available for the authors. This facility not only provides the prompt publications of the manuscripts but at the same time also early availability of the manuscripts for the readers.
Indexation and online availability: Indexation transforms the journal in some sense from its local ownership to the worldwide professional community and to the public.JCDR is indexed with Embase & EMbiology, Google Scholar, Index Copernicus, Chemical Abstracts Service, Journal seek Database, Indian Science Abstracts, to name few of them. Manuscriptspublished in JCDR are available on major search engines ie; google, yahoo, msn.
In the era of fast growing newer technologies, and in computer and internet friendly environment the manuscripts preparation, submission, review, revision, etc and all can be done and checked with a click from all corer of the world, at any time. Of course there is always a scope for improvement in every field and none is perfect. To progress, one needs to identify the areas of one's weakness and to strengthen them.
It is well said that "happy beginning is half done" and it fits perfectly with JCDR. It has grown considerably and I feel it has already grown up from its infancy to adolescence, achieving the status of standard online e-journal form Indian continent since its inception in Feb 2007. This had been made possible due to the efforts and the hard work put in it. The way the JCDR is improving with every new volume, with good quality original manuscripts, makes it a quality journal for readers. I must thank and congratulate Dr Hemant Jain, Editor-in-Chief JCDR and his team for their sincere efforts, dedication, and determination for making JCDR a fast growing journal.
Every one of us: authors, reviewers, editors, and publisher are responsible for enhancing the stature of the journal. I wish for a great success for JCDR."
Thanking you
With sincere regards
Dr. Rajendra Kumar Ghritlaharey, M.S., M. Ch., FAIS
Associate Professor,
Department of Paediatric Surgery, Gandhi Medical College & Associated
Kamla Nehru & Hamidia Hospitals Bhopal, Madhya Pradesh 462 001 (India)
E-mail: drrajendrak1@rediffmail.com
On May 11,2011
Dr. Shankar P.R.
"On looking back through my Gmail archives after being requested by the journal to write a short editorial about my experiences of publishing with the Journal of Clinical and Diagnostic Research (JCDR), I came across an e-mail from Dr. Hemant Jain, Editor, in March 2007, which introduced the new electronic journal. The main features of the journal which were outlined in the e-mail were extensive author support, cash rewards, the peer review process, and other salient features of the journal.
Over a span of over four years, we (I and my colleagues) have published around 25 articles in the journal. In this editorial, I plan to briefly discuss my experiences of publishing with JCDR and the strengths of the journal and to finally address the areas for improvement.
My experiences of publishing with JCDR: Overall, my experiences of publishing withJCDR have been positive. The best point about the journal is that it responds to queries from the author. This may seem to be simple and not too much to ask for, but unfortunately, many journals in the subcontinent and from many developing countries do not respond or they respond with a long delay to the queries from the authors 1. The reasons could be many, including lack of optimal secretarial and other support. Another problem with many journals is the slowness of the review process. Editorial processing and peer review can take anywhere between a year to two years with some journals. Also, some journals do not keep the contributors informed about the progress of the review process. Due to the long review process, the articles can lose their relevance and topicality. A major benefit with JCDR is the timeliness and promptness of its response. In Dr Jain's e-mail which was sent to me in 2007, before the introduction of the Pre-publishing system, he had stated that he had received my submission and that he would get back to me within seven days and he did!
Most of the manuscripts are published within 3 to 4 months of their submission if they are found to be suitable after the review process. JCDR is published bimonthly and the accepted articles were usually published in the next issue. Recently, due to the increased volume of the submissions, the review process has become slower and it ?? Section can take from 4 to 6 months for the articles to be reviewed. The journal has an extensive author support system and it has recently introduced a paid expedited review process. The journal also mentions the average time for processing the manuscript under different submission systems - regular submission and expedited review.
Strengths of the journal: The journal has an online first facility in which the accepted manuscripts may be published on the website before being included in a regular issue of the journal. This cuts down the time between their acceptance and the publication. The journal is indexed in many databases, though not in PubMed. The editorial board should now take steps to index the journal in PubMed. The journal has a system of notifying readers through e-mail when a new issue is released. Also, the articles are available in both the HTML and the PDF formats. I especially like the new and colorful page format of the journal. Also, the access statistics of the articles are available. The prepublication and the manuscript tracking system are also helpful for the authors.
Areas for improvement: In certain cases, I felt that the peer review process of the manuscripts was not up to international standards and that it should be strengthened. Also, the number of manuscripts in an issue is high and it may be difficult for readers to go through all of them. The journal can consider tightening of the peer review process and increasing the quality standards for the acceptance of the manuscripts. I faced occasional problems with the online manuscript submission (Pre-publishing) system, which have to be addressed.
Overall, the publishing process with JCDR has been smooth, quick and relatively hassle free and I can recommend other authors to consider the journal as an outlet for their work."
Dr. P. Ravi Shankar
KIST Medical College, P.O. Box 14142, Kathmandu, Nepal.
E-mail: ravi.dr.shankar@gmail.com
On April 2011 Anuradha
Dear team JCDR, I would like to thank you for the very professional and polite service provided by everyone at JCDR. While i have been in the field of writing and editing for sometime, this has been my first attempt in publishing a scientific paper.Thank you for hand-holding me through the process.
Dr. Anuradha
E-mail: anuradha2nittur@gmail.com
On Jan 2020
Case report
Full Version
Multifocal Gingival Squamous Cell Papilloma: A Case Report and Literature Review
Correspondence Address :
Dr. Shikha Tewari,
Senior Professor, Department of Periodontics, Post Graduate Institute of Dental Sciences, Rohtak-124001, Haryana, India.
E-mail: drshikhatewari@yahoo.com
Squamous Cell Papilloma (SCP) is a benign, asymptomatic, exophytic cauliflower-like growth of mucosal mass. It is mostly associated with Human Papilloma Virus (HPV) subtypes 6 and 11, and has a very low virulence and infectivity rate. The papillomas are commonly known as warts or verrucas when found on the skin. The typical lesion is a single mass with finger-like extensions, resembling a soft, pedunculated growth supported by a stem or stalk. If keratin, a skin protein, accumulates around the lesion, the projections can be long and pointed or short and rounded. Intraorally, the most common sites of occurrence are the tongue, lips, buccal mucosa, palate, and uvula. Hereby, the author present a case report of 25-year-old male patient with a 4×9 mm exophytic growth exhibiting a pebbled surface in the upper left first premolar region, with no signs of radiographic bone loss. Additionally, smaller pinpoint lesions were observed bilaterally in the interdental region of the first and second maxillary molars. A nevus on the right side of the face was also noted. Histological analysis confirmed the diagnosis of SCP. The presence of multifocal gingival squamous papilloma, along with an extraoral nevus, represents a novel finding that warrants reporting. The gingival lesion in the maxillary left first premolar region was surgically excised, along with 1 mm of healthy surrounding gingiva. This resulted in complete healing, and no recurrence was observed during the 12-month follow-up period.
Benign neoplasm, Human papilloma virus, Oral cavity
A 25-year-old male patient reported mild intermittent pain and irritation in the gums while chewing hard food in the upper left-side region for the past six months. The dental and medical history were non contributory. Intraoral clinical examination revealed a pinkish, exophytic sessile growth measuring 4×9 mm with a pebbled surface on the facial marginal and attached gingiva in the maxillary left first premolar region. The lesion did not involve the mucogingival junction. The surrounding gingiva appeared normal, with no bleeding on probing and a pocket depth of 3 mm around the same tooth. Similar solitary pinpoint lesions were observed bilaterally in the interdental papillary region of the first and second maxillary molars (Table/Fig 1)a-d. Extraorally, a hard and sessile nevus measuring 8×9 mm was present on the right side of the face, lateral to the nostril. The nevus was non-painful and had been present since birth, as reported by the patient (Table/Fig 1)e.
No intervention was performed for the extraoral nevus at this point. The patient was advised and referred to a surgeon for an opinion. However, the patient expressed disinterest in seeking treatment for the nevus. Regarding the gingival lesions, no radiographic bone loss was evident in relation to the maxillary left first premolar or the interdental area between the first and second maxillary molars on either side (Table/Fig 2)a-c.
A provisional diagnosis of gingival squamous papilloma was made, with differential diagnoses including papillary hyperplasia, verruciform xanthoma, condyloma acuminatum, and verruca vulgaris. Excisional biopsy was planned for the exophytic tissue present on the mid-buccal surface of the maxillary left first premolar, while the pinpoint lesions were left untreated. The patient provided written informed consent after the procedure was explained. Complete haemogram levels were within normal limits, and full mouth scaling and root planing were performed. The biopsy was conducted in accordance with the ethical standards outlined in the 1975 Declaration of Helsinki, as revised in 2013. Under local anaesthesia, the lesion was excised along with 1 mm of surrounding healthy gingiva (Table/Fig 3)a-c using a No.15 Bard Parker (BP) blade, and periodontal dressing* was applied to the site. The excised tissue was sent for histopathological {Haematoxylin and Eosin (H&E)}.
Histological features included hyperkeratinised stratified squamous epithelium projecting as finger-like papillary projections with fibrovascular cores. Some fibrovascular cores showed hyalinised stroma. The underlying stroma exhibited small and large vascular channels and a moderate amount of inflammatory cell infiltrate, predominantly lymphocytes. Additionally, koilocytes were also observed (Table/Fig 4)a-c. These findings confirmed the diagnosis of gingival SCP.
Following the surgery, the patient was recalled after one week for evaluation, and the healing process was uneventful. Follow-up examinations at 1, 6, and 12 months showed no signs of recurrence (Table/Fig 5)a,b.
Squamous Cell Papilloma (SCP) is a benign exophytic growth characterised by localised verrucous or cauliflower-like proliferation. The aetiology of SCP includes mechanical and chemical irritation and/or infection with HPV subtypes 6, 11, and 16, with HPV 6 and 1311 having low oncogenic potential (1). SCP is the fourth most common oral mucosal lesion, accounting for 4 in 1000 of all biopsied lesions (2). It often occurs in the age group between 30-50 years with a higher predilection in males. HPV lesions are infectious, but SCPs have an extremely low virulence and infectivity rate (1).
Squamous Cell Papillomas (SCP) most commonly occurs on the vermillion of the lips, hard and soft palate, with a high predilection for the uvula (3). However, its occurrence on the gingiva is relatively rare (3),(4). This case report presents a case of multifocal gingival squamous papillomas, with a lesion on the keratinised mid-buccal gingiva in relation to the upper left first premolar, smaller pinpoint lesions bilaterally in the interdental region of the first and second maxillary molars, and a nevus on the right side of the face lateral to the nostrils. Basal cells of the gingival epithelium are considered one of the possible reservoirs of latent HPV infection (5). The aetiopathogenesis of squamous papilloma of the gingiva could be explained by the presence of local irritation or persistent inflammation of the gingiva, leading to increased epithelial cell division, which further aids in HPV replication (5).
The current case presents a squamous papilloma involving the marginal and attached gingiva of the maxillary left first premolar. Although no radiographic bone loss was evident. Histopathologically, SCPs present as characteristic finger-like projections showing hyperkeratosis, with a fibrovascular core and a hyalinised stroma containing a marked granular cell layer. Koilocytes may or may not be seen. Under conditions of chronic irritation or trauma, small foci of lymphocytes can be observed at the base of the lesion (3). In the present case report, the patient complained of gum irritation during mastication, and clinical findings revealed multifocal exophytic gingival lesions along with a nevus on the face. Furthermore, histological findings demonstrated typical features of SCP, along with the presence of lymphocytes and koilocytes. All these findings pointed towards a viral aetiology. Differential diagnoses of squamous papilloma may include papillary hyperplasia, verruciform xanthoma, condyloma acuminatum, and verruca vulgaris (6). The limitation of the present case report includes the absence of advanced techniques such as Polymerase Chain Reaction (PCR), comet assay, and DNA Break Detection/Fluorescence in-situ Hybridisation (DBD-FISH) testing to confirm HPV involvement. Treatment of squamous papilloma includes surgical excision in toto, including the base of the lesion and a small area of marginal tissue. Laser treatment has also been proposed as an alternative treatment option to surgical scalpel in the literature (7). Recurrence of SCP is relatively rare, except for Human Immunodeficiency Virus (HIV) infected lesions (8).
Literature review: In a review of the literature a case report showed the presence of a cauliflower-like growth 6x10 mm with tiny finger-like projections on the facial aspect of the mandibular left second premolar, involving the keratinised gingiva with mild crestal bone loss (Table/Fig 6) (1),(4),(9),(10),(11),(12),(13),(14),(15).
The lesion present in the maxillary left first premolar region was surgically excised along with 1 mm of healthy surrounding gingiva, resulting in a complete healing. No signs of recurrence were observed during the 12-month follow-up period.
DOI: 10.7860/JCDR/2023/64086.18337
Date of Submission: Mar 18, 2023
Date of Peer Review: Apr 24, 2023
Date of Acceptance: May 23, 2023
Date of Publishing: Aug 01, 2023
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. Yes
PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Mar 23, 2023
• Manual Googling: Apr 19, 2023
• iThenticate Software: May 17, 2023 (10%)
ETYMOLOGY: Author Origin
EMENDATIONS: 5
- Emerging Sources Citation Index (Web of Science, thomsonreuters)
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